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Are Emulsifiers Bad for Gut Health? You Might be Surprised by the Answer.

Evidence Based

iHerb has strict sourcing guidelines and draws from peer-reviewed studies, academic research institutions, medical journals, and reputable media sites. This badge indicates that a list of studies, resources, and statistics can be found in the references section at the bottom of the page.

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Key Takeaways

  • Emulsifiers are ingredients used to help blend oil- and water-based components: They’re commonly found in processed foods, dressings, ice cream, and packaged products.
  • Different emulsifiers serve different functions: Lecithin, carrageenan, polysorbates, and gums are among the ingredients used to affect texture and stability.
  • Researchers are studying how some emulsifiers may affect gut health: Certain additives have been explored in relation to the gut microbiome and intestinal lining.
  • Not all emulsifiers are viewed the same way: Source, processing method, and amount used can vary significantly between ingredients and products.
  • Overall dietary patterns still matter: Emulsifiers are one part of a broader conversation around ultra-processed foods and long-term eating habits.

You’re on your weekly shopping trip. You reach for a loaf of whole-wheat bread and flip it over to check the ingredients. It seems healthy enough—until you spy “soy lecithin.”

“Wait,” you think. “Isn’t it bad for me? What’s it doing in whole-grain bread?”

Soy lecithin is just one in a class of ingredients called emulsifiers that have come under scrutiny for their possible negative impacts, particularly on gut health. A recent report from the U.S. Department of Health & Human Services (HHS) called out emulsifiers for their potential to disrupt the microbiome, damage the intestinal lining, and trigger inflammation.

Yet these additives are widespread in the food system. As one of the most common ingredients in packaged foods, particularly ultra-processed foods, emulsifiers probably show up on your plate more often than you realize.

Why Are Emulsifiers in Food?

Emulsifiers have a purpose: to form a suspension between liquids that wouldn’t normally mix, typically water and oil. Emulsifying ingredients create a border between the liquids so the suspension, called an emulsion, stays stable.

Forming emulsions in food helps prevent ingredients from separating, extends shelf life, and improves texture and flavor. It’s the reason why, for example, that bottle of salad dressing you forgot about in the back of your cabinet never became a solid mass of cream with three inches of oil floating on top.

The Most Common Types of Emulsifiers

Emulsifiers can be natural or man-made. Natural emulsifiers have been used in food since the days of ancient Greece, but synthetic emulsifiers didn’t become widespread until the late 20th century. Over 170 of these ingredients are currently used as food additives in the United States in everything from ice cream, salad dressing, and cream sauces to bread, chocolate, and nut butters.

The FDA maintains a detailed database of emulsifying ingredients, but these are the ones you’ll most commonly see in food labels:

  • Carrageenan
  • Celluloses
  • Gelatin
  • Guar gum
  • Lecithin (soy, sunflower)
  • Mono- and diglycerides
  • Polysorbate 60
  • Polysorbate 65
  • Polysorbate 80
  • Propylene glycol
  • Xanthan gum

Over half the calories consumed at home in the U.S. come from ultra-processed foods that often contain one or more of these ingredients.

Are Emulsifiers Bad for Gut Health?

Whether consuming emulsifiers can disrupt gut health is up for debate. Regulatory bodies like the U.S. Food and Drug Administration (FDA) and the EU European Food Safety Authority (EFSA) assess the safety of emulsifying ingredients and assign each an acceptable daily intake (ADI) limit—the amount you can eat in a day without potentially negative effects.

Regardless of the ADI, many emulsifiers aren’t absorbed during digestion, so they may travel to your gut and interact with your microbiome. Some of these interactions appear to promote changes in the gut’s environment and structure.

How Food Emulsifiers Affect the Gut

Recent studies of emulsifiers like carboxymethylcellulose (CMC), polysorbate 80, DATEM, lecithin, and gums suggest that these additives have the potential to cause long-lasting or non-reversible effects in the gut microbiome, including:

  • Reduced density (the overall number of bacteria), richness (the total number of bacterial species), and diversity (the range of different kinds of bacteria)
  • Reduced levels of beneficial microbes like Lactobacillus, Faecalibacterium, and Akkermansia
  • Increased pathogenic bacteria like Escherichia coli and Shigella
  • Bacterial imbalances or overgrowth (dysbiosis)
  • Altered expression of bacterial genes

Emulsifiers may also cause changes in the layer of mucus that protects the gut lining and the junctions between cells in the gut barrier. Together, these effects can alter gut function and lead to problems like systemic inflammation, colitis, blood sugar imbalances, increased fat mass, and non-alcoholic fatty liver disease (NAFLD).

Additional evidence suggests that emulsifier consumption may be linked to:

  • Cardiovascular disease
  • Type 2 diabetes
  • Certain types of disease, including breast and prostate

These associations were discovered through the French NutriNet-Santé cohort study, which has been assessing the connection between nutrition and health in a group of over 100,000 people since 2009.

Does Avoiding Emulsifiers Improve Gut Health?

However, many studies on emulsifiers have been done either in animals or in simulations of the human gut. The limitations of these studies make it difficult to determine whether eliminating emulsifiers from your diet is necessary for gut health.

Different emulsifiers appear to impact the gut in different ways, and some don’t cause any noticeable changes. Certain emulsifiers have even been linked to health benefits, including lower pro-inflammatory markers, improved gut barrier structure, and increased numbers of beneficial bacteria. These mixed results may be due to factors like dietary habits and the amounts and types of bacteria in the microbiome, which can influence how emulsifiers impact the gut.

Adjusting Your Diet to Reduce Emulsifiers

Rather than driving yourself crazy trying to eliminate every emulsifier from your diet, focus on swapping ultra-processed foods with more whole and minimally processed foods. Making these changes reduces your intake of ingredients associated with poor gut health, increased inflammation, and chronic disease, and fills your plate with more high-fiber, anti-inflammatory foods that support a balanced microbiome and strong intestinal barrier.

To get started with a more gut-friendly diet:

  • Experiment with a wide range of vegetables, whole grains, beans, nuts, seeds, fruits, and seafood
  • Cook more food at home instead of eating out
  • Make your own condiments, sauces, and salad dressings from simple ingredients you already have around the house
  • Look for minimally processed alternatives to snacks, desserts, and other treats (Hint: Fruit makes a great snack!)

As for that whole wheat bread, whether you put it back is up to you. But it’s likely that you don’t have to be concerned about the emulsifier if the majority of your diet focuses on foods that promote a healthy gut.

So go enjoy a sandwich! 

References: 

  1. Chassaing, B., Van de Wiele, T., De Bodt, J., Marzorati, M., & Gewirtz, A. T. (2017). Dietary emulsifiers directly alter human microbiota composition and gene expression ex vivo in a way that increases pro-inflammatory potential. Gut, 66(8), 1414–1427.
  2. Elizabeth, L., Machado, P., Zinöcker, M., Baker, P., & Lawrence, M. (2021). Ultra-processed foods and health outcomes: A narrative review. Nutrition Reviews, 79(6), 726–743. 
  3. European Food Information Council. (2023). Common uses of emulsifiers in food: Food safety and function. EUFIC Food Science Series.
  4. KFF Health News Editorial Board. (2025). Review of synthetic compounds and texturizers in ultra-processed foods (HHS Policy White Paper No. 2025-05). Henry J. Kaiser Family Foundation.
  5. Lane, M. M., Gamage, E., Du, S., Ashtari, S., S, C., & Jacka, F. N. (2023). Ultra-processed food exposure and adverse health outcomes: An umbrella review of epidemiological meta-analyses. The BMJ, 382, Article e076058. 
  6. LaRosa, E., & Howard, J. (2025, May 19). How food emulsifiers sneakily alter the gut microbiome. CNN Health and Wellness Features.
  7. Naimi, S., Viennois, E., Gewirtz, A. T., & Chassaing, B. (2021). Direct impact of commonly used dietary emulsifiers on human gut microbiota. Microbiome, 9(1), Article 66.
  8. Rauber, F., Chang, K., & Levy, R. B. (2024). Ultra-processed food consumption, metabolic syndrome, and type 2 diabetes risk: A multi-cohort analysis. The Lancet Diabetes & Endocrinology, 12(4), 234–246. 
  9. Sellem, L., Srour, B., Jackson, K. G., Kesse-Guyot, E., Chassaing, B., & Touvier, M. (2024). Food additive emulsifiers and risk of cardiovascular disease in the NutriNet-Santé cohort: Prospective cohort study. The BMJ, 384, Article e076005. 
  10. Srour, B., Chazelas, E., Druesne-Pecollo, N., Touvier, M., & PLOS Medicine Consortium. (2024). Quantitative assessment of dietary emulsifier intake and cancer risk: Results from the large-scale population-based NutriNet-Santé cohort. PLOS Medicine, 21(2), Article e1004338. 
  11. Taylor, S. L. (2012). Emulsifiers and texturizers in industrial food applications. In F. M. Clydesdale (Ed.), Food Science and Technology Monographs (pp. 211–234). Academic Press.
  12. Tellez, G., & Springer Science Group. (2008). Physical chemistry of emulsification and food matrix interactions. In J. N. Coupland (Ed.), Food Emulsifiers and Their Applications (3rd ed., pp. 1–28). Springer New York. 
  13. U.S. Food and Drug Administration. (2024). Substances added to food: Inventory of evaluated food ingredients and emulsifiers. FDA Human Food Program Database Portal.
  14. Walters, M. (2024). Ultra-processed foods account for more than half of calories consumed at home. Johns Hopkins Bloomberg School of Public Health Communications.
  15. Whelan, K., Bancil, A. S., & Lindsay, J. O. (2024). Ultra-processed foods and food additives in gut health and disease. Nature Reviews Gastroenterology & Hepatology, 21(6), 406–427. 
  16. Fusco, W., Lorenzo, M. B., Cintoni, M., Porcari, S., Rinninella, E., Kaitsas, F., Lener, E., Mele, M. C., Gasbarrini, A., Collado, M. C., Cammarota, G., & Ianiro, G. (2023). Short-chain fatty-acid-producing bacteria: Key components of the human gut microbiota. Nutrients, 15(9), Article 2211. 

DISCLAIMER: These statements have not been approved by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent disease.